MODIFIED METABOLIC SYNDROME

JPUMHS;2025:15:01,79-84. http://doi.org/10.46536/jpumhs/2025/15.01.599

Abstract

BACKGROUND: Metabolic syndrome refers to a set of clinical factors leading to a
multitude of complex multi-system complications. Derangement of phosphate homeostasis
may suggest a tendency towards metabolic syndrome. OBJECTIVE: To determine the
frequency of hypophosphatemia in patients with metabolic syndrome METHODOLOGY:
A cross-sectional study undergone from February to August 2024 upon a sample of 150
consenting adults of either gender, diagnosed with Metabolic syndrome lasting ≥ 6- weeks
duration having age 30-60 years presenting at Liaquat University Hospital, Hyderabad,
Pakistan. Data was composed on predesigned proforma and the frequency (percentage)
and mean ± SD was calculated for qualitative and quantitative variables. RESULTS:, Of
the study sample, hypophosphatemia was noted in 90 (60%) patients, from which 49
(54.4%) were males and rest were females .The statistical significance was analyzed for
hypophosphatemia in accordance with age (p=0.00), residence (p=0.00), duration of
metabolic syndrome, (p=0.03), smoking (p=0.02), obesity (p=0.03), hyperlipidemia
(p=0.02), hypomagnesemia (p=0.00), hyperuricemia (p=0.00) and uncontrolled diabetes
mellitus (p=0.00) while in context to gender it was observed as non-significant
(p=0.13).CONCLUSION: There was a significant association of hypophosphatemia
among patients with metabolic syndrome, with significant association with regards to
various patient demographic and clinical data.