SERO-PREVALENCE OF HELICOBACTER PYLORI INFECTION IN PATIENTS INFECTED WITH HEPATITIS C VIRUS WITH AND WITHOUT LIVER CIRRHOSIS.

Abstract

Objective: To determine the sero-prevalence of helicobacter pylori infection in patients infected with hepatitis c virus infection with and without liver cirrhosis. Study Design: Descriptive analytical study Setting: The department of Gastroenterology unit, Isra University hospital, Hyderabad. Duration: From 4thMarch 2016to 3rd September 2016. Material and Methods: All the hepatitis C infected patients with and without liver cirrhosis, irrespective of treatment and either of gender was included in the study. Severity of liver cirrhosis was assessed by child Pugh classification. Blood samples were taken from all study subjects and were sent to the Hospital diagnostic laboratory to assess the pylori infection serologically. All the data was recorded via study proforma. Data was analyzed by using SPSS version 20. Results: Total 385 patients were studied their mean age was 55.45±12.19 years. Out of all 223were males and 162 were females. Liver cirrhosis was found 69.4% out of all study subjects. The H. Pylori infection was found to be 89.1%. The H. pylori infection was significantly associated to patients having cirrhosis of liver (p=0.011).Conclusion: H. Pylori infection was significantly more prevalent among HCV cirrhotic patients as compared HCV non-cirrhotic patients.