CLINICO-EPIDEMIOLOGICAL PRESENTATION AND OUTCOME OF COVID-19 INFECTED PATIENT IN HYDERABAD, PAKISTAN.

Abstract

ABSTRACTObjective:To demonstrate the variability of clinical presentation and outcome of corona virus disease 2019 (COVID-19) infected patients in Liaquat University Hospital, Jamshoro.Methods:Observationalprospective study was conducted from April-May 2020. Patients admitted in Liaquat University Hospital and confirmed as Covid-19 infected patients after real-time polymerase chain reaction test, irrespective of their age, gender and given consent of participation were included in the study. While patients with negative tests findings were excluded from the study. Epidemiological, clinical, laboratory and radiological data were collected. All the data was analyzed statistically using SPSS ver. 23. Results:Most(56.25%) of the patients were male and 73.66% of the participants were residing in urban areas. Two-third (77.67%) had a history of having direct contact with COVID infected persons.Moreover, 73.66% patients were presented without any COVID symptoms. Persistent dry cough (81.35%) was amongst the top symptom among the symptomatic cases followed by high grade fever (59. 33%).Among the comorbidities, hypertension was the most common (17.85%)comorbidity followed by chronic obstructive pulmonary disease (17.65%).Among the laboratory findings, Leukopenia was observed in 20.98% patients while lymphopenia was observed in 12.05%. Complications were observed in 11.16% patients. The most common complication observed was Acute respiratory distress syndrome and acute kidney injury. Conclusion:COVID-19 is affecting younger adult (20-39 years), male, from urban area predominantly. Persistent dry cough &high grade fever are the more common symptoms. Moreover, Acute Respiratory Distress Syndrome and acute kidney injury are the most common complications