COMPARISON OF OUTCOME OF 0.5% HYPERBARIC BUPIVACAINE WITH 0.5% HYPERBARIC ROPIVACAINE IN SPINAL ANAESTHESIA FOR PERIANAL SURGERIES.
Keywords:Keywords: Hyperbaric bupivacaine, ropivacaine, spinal anaesthesia
Introduction: The field of anaesthesiology has undergone significant advancements in recent
years, resulting in improved patient outcomes and reduced hospitalization durations. This is
primarily due to the availability of anaesthetic agents that block sensations locally or regionally
for shorter durations. Objective: To compare the outcome of 0.5% hyperbaric Ropivacaine with
0.5% hyperbaric Bupivacaine in spinal anaesthesia for perianal surgeries. Design: Randomized
controlled trial. Setting: Anaesthesiology Department, Surgical Intensive Care Unit And Pain
Management, Jinnah Post graduate Medical Centre (JPMC), Karachi. Duration: Six months
(From 7 April 2016 to 7 October 2016). Methods: 126 Perianal surgery patients were
approached for consent for study. Two groups viz; A & B were made, and group allocation of
consecutive patients were made through using opaque envelopes containing strip of either group.
Group A patients received three mililiter of Ropivacaine (5 mg/ml) with glucose 83 mg/ml.
Whereas, Group B received three mililiter of hyperbaric Bupivacaine (5 mg/ml) with glucose 80
mg/ml. Moreover, Oral temazepam 10–20 mg was administered to patients before to surgery to
reduce anxiety. Results: The duration of sensory block was statistically less in the Ropivacaine
group (153.8±9.3min) as compared to Bupivacaine group (190.2±8.3min) with P-value 0.0001.
In addition, the ropivacaine group's mean time in motor block was less than that of the
bupivacaine group (120.89±12.122 min vs 189.33±11.947min; P = 0.0001). Conclusion:
According to the results of the current investigation, bupivacaine applied intrathecally causes
sensory block to begin more quickly and last longer than ropivacaine.
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