@article{Mubashara Murtaza1 , Kiran Ashfaq Ahmed2 , Maryam Abbasi3 , Aalya Farooq4 , Momina Shafique5 , Naheem Ahmed6_2023, title={PREVALENCE OF HEPATIS B AND C AMONG BETA THALASSEMIA MAJOR PATIENTS AT A TERTIARY CARE HOSPITAL: http://doi.org/10.46536/jpumhs/2023/13.01.405}, volume={13}, url={http://publication.pumhs.edu.pk/index.php/ojs/article/view/724}, abstractNote={<p>ABSTRACT</p> <p>Introduction: The beta-thalassemia are among the most prevalent hereditary diseases, and they</p> <p>influence the lives of millions of children all over the world. Because appropriate viral screening</p> <p>of donated blood has never been carried out, the infection risk in -thalassemia individuals serve</p> <p>as a signal for the hazard of transfusion-transmitted illnesses, specifically hepatitis B and C as</p> <p>well as other viral infections. Objective: To determine the prevalence of hepatitis B and C</p> <p>among beta-thalassemia major patients at a tertiary care Hospital.Material and methods: This</p> <p>descriptive cross-sectional study was done at the pediatric department at SKBZ/AK, CMH</p> <p>Hospital Muzaffarabad, during a period of six months from October 2019 to March 2020. All the</p> <p>beta thalassemia major patients, aged up to 15 years, and both genders, were included. Following</p> <p>informed consent, a 3-5 mL blood sample was collected from each case and immediately sent to</p> <p>the hospital diagnostic laboratory to screen for HCV and HVB infections using the Elisa method.</p> <p>All the informatiosn was collected via a study proforma, and SPSS version 26 was used for data</p> <p>analysis.Results: A total of 87 patients with beta thalassemia major were studied; their mean age</p> <p>was 10.0+3.68 years. Males were 55.8% and females were 44.8%. Out of all 35.6% patients were</p> <p>infected by HCV, while only one patient found with HCV and HBV co-infection. As per the</p> <p>stratification, HCV infection was significantly linked to age more than 10 years (p-0.001), while</p> <p>statistically insignificant according to gender (p-0.344). Conclusion: As per the study</p> <p>conclusion, HCV infection was observed to be highly prevalent among patients with beta￾thalassemia major. It was positively related to the blood transfusions. Unfortunately, due to the</p> <p>high incidence of these viruses in individuals with beta thalassemia, it would appear that the</p> <p>precautions used in blood preparation and testing to prevent infections that are transferred by</p> <p>blood transfusion are still insufficient.</p>}, number={1}, journal={Journal of Peoples University of Medical & Health Sciences Nawabshah. (JPUMHS)}, author={Mubashara Murtaza1 , Kiran Ashfaq Ahmed2 , Maryam Abbasi3 , Aalya Farooq4 , Momina Shafique5 , Naheem Ahmed6}, year={2023}, month={Mar.}, pages={194–199} }