ASSOCIATION OF SPONTANEOUS HEPATIC ENCEPHALOPATHY IN HIGH PROTEIN DIET CONSUMER PATIENTS OF CHRONIC LIVER DISEASE.
Keywords:CLD, encephalopathy, rich protein diet.
OBJECTIVE: To determine the association of spontaneous hepatic encephalopathy in high protein diet
consumer patients of chronic liver disease CLD. STUDY SETTING: This descriptive study was carried
out at gastroenterology department of Asian Institute of Medical Sciences Sindh Pakistan. STUDY
DURATION: Six months from April 2019 to October 2019. METHODS: All the individuals admitted in
the gastroenterology department with hepatic encephalopathy, of any gender who were 18 years of age or
older were included. After takin complete medical history and clinical examination, patients were evaluated
regarding rich protein diet consumption to observe the high protein diet consumption as a critical element
in the development of hepatic encephalopathy. The information was gathered exclusively through a study
proforma, and data analysis was conducted using SPSS version 26. RESULTS: A total of 92 patients of
hepatic encephalopathy with average age of 54.36+11.3 years with male predominance were studied.
Hepatitis C was the commonest etiological factors of the chronic liver disease. High-protein diet exhibited
a reduced occurrence of hepatic encephalopathy, with rates of 3.3% for grade-I, 7.6% for grade-II, 4.3%
for grade-III, and 4.3% for the grade-IV, in contrast to the usual diet group. Fewer patients in the high
protein diet group experienced infection 3.3% compared to the usual diet group 34.8% p-0.050.
Furthermore, the high protein diet group showed the significantly lower rate of AKI 1.1% compared to the
usual diet group 23.9%, p- 0.034. CONCLUSION: Hepatic encephalopathy and other complications were
highly prevalent in low protein diet compared to the rich protein diet. It was observed that the rich best
nutritional diet is decrease the disease prognosis compared to the formal diet.
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