PATHOGENS CAUSING NEONATAL SEPSIS AT MCH HOSPITAL NAWABSHAH.

http://doi.org/10.46536/jpumhs/2024/14.02.517

Abstract

BACKGROUND : A particular kind of neonatal illness known as "neonatal sepsis" occurs when a newborn infant
has a bacterial blood stream infection (BSI) accompanied by a fever, such as meningitis, pneumonia,
pyelonephritis, or gastroenteritis. Neonatal sepsis is often referred to as "sepsis neonatorum" in older texts.
Clinically, criteria concerning hemodynamic compromise or respiratory failure are useless since these symptoms
often do not appear in newborns until death is certain and cannot be avoided. Early-onset sepsis (EOS) and lateonset sepsis (LOS) are the two subtypes of neonatal sepsis. Sepsis that manifests during the first 72 hours of life
is referred to as LOS, while sepsis that manifests after 7 days (or 72 hours, depending on the system employed) is
referred to as EOS. In underdeveloped nations, neonatal sepsis is the leading cause of infant mortality in both
hospitals and communities. OBJECTIVES: To identify the causative organism among neonatal sepsis maternal
MCH Hospital Nawabshah. MATERIAL METHODS: STUDY SETTINGS: The study was conducted at Paeds
Ward of MCH Nawabshah, SBA. Study Population: Data was collected from patients at MCH Nawabshah, SBA.
STUDY DESIGN: Cross-Sectional Study. Duration of study: June 2023-December 2023. SAMPLE SIZE: 285
RESULTS: E Coli was found in 90(31.5%), Klebshiella in 37 in 13%, S.Aureus in 18(6.3%), H.influenza in
15(5%), Pseudomonas Aueroginosa in 4 (1.4%), Group B Streptococcus in 30(10.5%) and V. Streptococcus in
6(2.3%). Total patients in which blood culture was positive were 200(70%) and 85(30%) had no growth.
CONCLUSION: It is concluded that neonatal sepsis is more common in low birth weight and most of neonates
were premature (before 37 weeks of gestation). E. coli and Staph Aureus were the most common organism
involved in developing neonatal sepsis.