Prevalence of Hepatitis Delta Virus (HDV) Infection In Hepatitis B virus Surface Antigen (HbsAg) Positive Subjects.

Abstract

OBJECTIVE: To   work   out the   pervasiveness   of hepatitis delta virus infection amongst HBsAg (Hepatitis B virus surface antigen)                                         positive                                         patients. Setting: Current  research was piloted  in Department  of Medicine at                      Peoples                   University         hospital       Nawabshah. Duration: Six Months (from September, 2017 to March, 2018). Study design: Current study was a Cross sectional. Subjects and Method:  After  approval  of study from the school of Physicians and Surgeons of Pakistan, a written consent was taken from the

155   subjects   attending    inpatient    or   outpatient    department of internal medicine in PMCH Nawabshah. Demographic detail (including name,  age  and gender)   were   obtained.   All those that fulfi ll the inclusion criterion were included in study otherwise were excluded. Exclusion criteria were followed strictly to avoid   confounding   variables.   Brief   history regarding hepatitis B and D and duration of  hepatitis  B and  D were taken. The appropriate investigations of the subjects  like serum anti-HDV by ELISA also as HBsAg (Hepatitis B surface antigen) were send to the institutional laboratory.

RESULTS: The average  age  of the  subjects was 44.6ñ10.2 (20 60)  years.  Out  of  total  155  subjects  54.2%  (84)  were  male

subjects and 45.8% (71) were female subjects. 127 (81.9%) HBV patients        had delta               hepatitis virus. Conclusion: It is concluded that prevalence   of hepatitis D disease is high in   subjects affected   by hepatitis B   infection.