ASSESSMENT OF PATIENTS HAVING ACUTE EXACERBATION OF BRONCHIECTASIS AND FACTORS LEADING TO MORTALITY IN THE HOSPITALIZED PATIENTS AT PULMONOLOGY DEPARTMENT JINNAH POSTGRADUATE MEDICAL CENTRE KARACHI.

Abstract

Abstract

ABSTRACT INTRODUCTION: Bronchiectasis is a pathological dilation of the bronchi and bronchioles produced by the disintegration of the elastic and muscular elements of the walls of bronchi and bronchioles. OBJECTIVES: The purpose of this study is to assess the frequency of fatalities in subjects admitted with diagnosis of acute exacerbations of bronchiectasis and to evaluate the prevalence of factors responsible for fatality in these admitted subjects, at Jinnah Postgraduate Medical Centre Karachi Pulmonology Unit. MATERIALS AND METHODS: Descriptive case series study. The research was carried out at the Jinnah Postgraduate Medical Centre Karachi Pulmonology Unit. Overall 140 subjects were selected in Jinnah Postgraduate Medical Centre Karachi Pulmonology Unit.  All those patients fulfilling the inclusion criteria were selected in the study. A short background of the disease's length was taken, as well as a clinical assessment, and written informed consent was obtained. To assess the factors those contribute to death throughout hospitalization and even after discharges for all patients until the end of the fourmonth follow-up period. RESULTS: Mean and standard deviation of age was 47.59±10.96 years. Male were 78(55.7%) and female were 62(44.3%). 87(62.1%) patients did not survived and 53(37.9%) patients were survived from the disease. factors of mortality were compared with mortality CONCLUSION: In conclusion, our study identified male gender, history of smoking, steroid use during hospitalization and mechanical ventilation need as independent factors for mortality in AEB patients.