BASIL SEEDS (OCIMUM BASILICUM) EFFICACY IN THE MANAGEMENT OF HYPERLIPIDEMIA.

Abstract

ABSTRACT

INTRODUCTION: Coronary heart diseases (CHD) are the leading cause of morbidity throughout the

World irrespective of gender. CHD can be prevented by proper management of hyperlipidemia in

aggregation with healthy diet and lifestyle. OBJECTIVE: The current study was designed to ascertain

the effect of basil seeds (Ocimum basilicum) on hyperlipidemia. METHODS: The study was carried

out at the University Institute of Diet & Nutrition Sciences, Faculty of Allied Health Sciences,

University of Lahore and Major Aziz Bhatti Teaching Hospital (DHQ) Gujrat, Punjab, Pakistan for one

year from April, 2021 to April, 2022. Sixty (60) cardiovascular patients from both genders, having

cholesterol level ≥ 200 mg/dL were selected and divided into three groups, one group of twenty (20)

patients was given no treatment (G0), second group of twenty (20) patients (G1) was given 5.0 g basil

seeds per patient per day and third group of twenty (20) patients (G2) was given 10.0 g basil seeds for

ninety days. The data was recorded for bio mass index (BMI), total cholesterol (TC) and triglycerides

(TG) at 0, 45 and 90 days of study period. RESULTS: Both the doses of basil seeds significantly

decreased bio mass index (BMI) from 40.59 to 31.16 (23.22 %), total cholesterol (TC) from 267.77 to

223.64 mg/dl (16.48 %) and triglycerides level (TG) from 250.15 to 207.77 mg/dl (16.94 %) of

cardiovascular patients with P value of < 0.001 during the whole span of study. The basil seeds (@ 5.0

and 10.0 g per patient per day significantly reduced bio mass index (BMI), total cholesterol (TC) and

triglycerides (TG) of cardiovascular patients during 45 and 90 days. However, the effect of basil seeds

was observed sharper in case of 2nd dose i.e. 10.0 g of basil seeds per patient per day. CONCLUSION:

Basil seeds have significant effect on lowering bio mass index, total cholesterol and triglycerides levels

of cardiovascular patients.