Frequency of Pre-Diabetes in Patients Attending Medical Units in a Tertiary Care Hospital

Abstract

This Cross sectional study was conducted in Medical unit-57 of Liaquat University Hospital. Hyderabad with a. duration of one year (Jan-Dec 2009). Total 500 subjects aged either 45 year and above or if below 45 years than had another risk factor for diabetes like: Blood pressure >140/90, HDL cholesterol 35mg/dl or less, Triglyceride 250mgidl or more. history of first degree relative with diabetes, history of gestational diabetes or history of delivery of large baby (weighing more than 9 pounds) were enrolled for the study, All diagnosed patients of diabetes were excluded from study. Initially demographic information, history regarding first degree relative with diabetes, gestational diabetes and delivery of large baby were obtained. Later, a physical examination was performed, including measurement of blood pressure, body mass index and waist-to-hip ratio ( WHR). Fasting blood samples were drawn and analysed for glucose, triglyceride and HDL cholesterol. Blood samples were also obtained and analysed for oral glucose tolerance test. Fasting blood glucose (FBG) <100mg/d1 and blood glucose level in OGTT< I 40mg/d1 were considered normal, while FBG > 100mg/d1 but <126mg/d1 and / or OGTT level > 140 mg/d1 but <200mg/d1 was considered prediabetes, and FBG > 126 mg/d1 and / or OGTT > 200 mgidlwere considered diabetes. The collected data was analysed on SPSS version 17.0.