EFFECTS ON HAEMATOLOGICAL PARAMETERS OF CUCURBITA PEPO SEEDS IN RABBITS.

Abstract

ABSTRACT
BACKGROUND: Medicinal plants chemical constituents affect body systems.1,2 Cucrabitaceae
belongs to the plant family, generally believed as consisting of melons, cucurbits and pumpkin.
OBJECTIVE: Assessment of effects of cucurbita pepo (pumpkin) seeds on haematological
parameters in rabbits. DESIGN: Experimental study. PLACE: The study was conducted at the
Pharmacology Department PUMHSW Shaheed Benazirabad. DURATION 01st Jan 2020 to 31st
March 2020. MATERIAL METHODS: By observing standard criteria for inclusion and
exclusion of rabbits in study. Thirty rabbits were chosen in the study. Calculated quantity of
powder of pumpkin seeds as 250 and 500 mgs was given subsequently daily for sixty days to
study groups. Zero time had reading marked as day 1st. Thereafter further readings taken after
every 15th day for the two months. The samples were assessed at D and R Lab PUMHS Shaheed
Benazirabad. Blood CP analyzed through Automatic Hemoglobin Analyser. Data evaluated
statistically in groups as means by the correlated pairs T-test and SPSS 22.0 version. P-value
upto 0.05 considered significant. RESULT: Whilst compared the study groups (B and C) with
the control (A) group the mean Hb, RBC, HCT, MCV, MCH and MCHC values on day 0 were
found non significant statistically. An increasing increase was observed from day 15 to day 60 in
all blood parameters. As compared with the control group, all interpretations were highly
statistically significant. CONCLUSIONS: Pumpkin seed can be substituted by common
methods as good herb food source for the boosting hemoglobin marker. It does not carry side
effects of weight increase or non cooperation of patients wih medical treatment due to higher
cost or having adverse effect.