TO DETERMINE THE IMPACT OF TYPE-2 DIABETES MELLITUS ON THE OUTCOME AMONG PATIENTS HAVING COVID-19 AT PMC HOSPITAL NAWABSHAH.: http://doi.org/10.46536/jpumhs/2023/13.03.459

Authors

Nazia Arain1 , Bashir Ahmed Khurhro2 , Mir Tahir Hussain Talpur3 , Nasrullah Aamer 4 , Ashok Kumar Luhano5 , Qurat ul Ain Dahri6 , Areeba Batool

Type-2 diabetes mellitus, COVID-19, mortality, hypertension.

OBJECTIVE: To find out impact of type-2 diabetes mellitus T2DM on the outcome among patients having

COVID-19 at PMC hospital Nawabshah. STUDY DESIGN: A single center observational study. PLACE

AND DURATION OF THE STUDY: This study was conducted at PMC hospital NAWABSHAH from

1 st June 2020 to 30th December 2020. MATERIAL AND METHODS: A total of 120 patients aged above

18 years and diagnosed as COVID-19 positive were included. Demographic details along with presenting

features were recorded among all patients. Clinical examination, relevant laboratory investigations and

radiological studies were done. Presence of T2DM was noted according to ADA diagnostic criteria.

Qualitative data like gender, presenting complaints, comorbidities, complications and outcome were

represented as frequency and percentages. Quantitative data like age was represented as mean and standard

deviation. Impact of diabetes on the outcome was noted using chi square test. P-value<0.05 was taken as

significant. RESULTS: Out of a total of 120 patients, 107 89.2% were male and 13 10.8% female. Overall,

mean age was noted to be 44.56+15.57 years ranging between 18 to 78 years. Hypertension was the most

frequent comorbidity followed by T2DM 30 25.0%. Complications were reported among 64 5.3% patients

while acute lung injury or respiratory distress syndrome were the most frequent complication seen among

41 34.2% patients while septic shock was observed among 14 11.7%. Significant association of T2DM was

noted with the mortality p=0.004. Increasing age was found to have significant relationship with mortality

p=0.004. Male gender was also found to have significant relationship with mortality as 66.7% of T2DM

patients who died were males p=0.004. CONCLUSION: Type-2 diabetes mellitus was to have significant

association with mortality among COVID-19 infected patients. Increasing age and male gender were also

noted to have signification relation mortality

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