EFFECTS OF ESCITALOPRAM IN COMBINATION WITH VITAMIN C, VITAMIN E AND LEVOSULPRIDE IN THE MANAGEMENT OF DYSLIPIDEMIA IN PATIENTS WITH DEPRESSION.

http://doi.org/10.46536/jpumhs/2024/14.02.516

Abstract

BACKGROUND: The purpose of this study is to provide light on the possible effects of antidepressants,
especially Escitalopram, on the lipid profiles of persons suffering from depression, both as a solo treatment and
in conjunction with adjuvant medicines such as Vitamin C, Vitamin E, and levosulpiride. METHODOLOGY:
Study consist of four groups Escitalopram alone (Group A), Escitalopram + Vitamin C, Vitamin C + Vitamin E
and Vitamin C+ levosulpride given to patients with dyslipidemia and depression. The findings were analyzed on
lipid profile levels after two months of intervention RESULTS: In comparison to control group the levels of lipid
profile including total cholesterol levels, LDL levels, Triglyceride levels, and Very low density lipoprotein levels
were significantly reduced (p<0.05) in the treatment group whereas levels of High density lipoprotein were found
to be significantly increase (p<0.05) in the treatment group in comparing to control group CONCLUSION: This
study explores the manner in which alternative Escitalopram therapies and dietary supplements (Vitamin C,
Vitamin E, and Levosulpride) affect the lipid profiles of depressed individuals.